Complete Guide To Mercedes Rear Signal Acquisition SAM Control Module | VIN

April 21, 2026

Verification & ASIN List

This guide covers all products from your exclusive Amazon store page: https://www.amazon.com/s?k=Rear+Signal+Acquisition+SAM+Control+Module&me=A2ZP7MOPZ4NF7I&ref=nb_sb_noss (Seller ID: A2ZP7MOPZ4NF7I). All items on this page are Mercedes-Benz Rear Signal Acquisition & Actuation SAM Control Modules, which are the core control units for the entire electrical system at the rear of the vehicle.

What Is Rear SAM Control Module?

SAM = Signal Acquisition & Actuation Module. It is the core rear electrical control unit in the Mercedes-Benz CAN bus body system. It is responsible for controlling rear lights, door locks, tailgate, fuel level sensors, fuse box circuits, and vehicle body communication. Most SAM module failures are caused by trunk water leakage and circuit board corrosion.

Compatible Vehicle Models

Mercedes-Benz W164 ML-Class: ML320 / ML350 / ML450 / ML550 / ML63 AMG
Mercedes-Benz X164 GL-Class: GL320 / GL350 / GL450 / GL550
Mercedes-Benz W251 R-Class: R350
Production Year: 2006 – 2012

Full Interchangeable OEM Part Numbers (All Interchangeable Directly)

A1649004500
A1649006700
A1644405541
A1649006900
A1649005401
A1649005101
A1645408845
A1644405101
A1644404001
A1649004801
A1645408862
A1645400162
A1645402601
A1645403462
A1645403662
A1645405662
A1645406745
A1645407901
A1649002901
A164900290180

⚠️ Mandatory VIN Verification Before Purchase (Must Read)

Do NOT purchase directly before sending us your vehicle's 17-digit VIN number!

Mercedes-Benz Rear SAM modules are strictly matched to the vehicle's VIN, original equipment configuration (power tailgate, trailer hitch, lighting version, etc.). Even if the part number is the same, it may not be compatible with different VINs.

Find your 17-digit VIN on the driver's door pillar or dashboard.
Send the VIN to the seller to confirm compatibility.
The seller will match the correct corresponding SAM module and ASIN for you.
Place your order only after confirmation.

Purchasing without VIN verification will cause error codes, non-functional rear lights, vehicle battery drain, CAN bus communication abnormalities, and other issues.

Professional Installation Steps

Completely turn off the vehicle power and disconnect the negative battery terminal.
Location of the Rear SAM module: Inside the fuse box on the left side of the vehicle's trunk.
First, inspect and fix the trunk water leakage problem (the main cause of SAM damage).
Take photos to record the original part number and plug wiring layout before removal.
Carefully unplug all wiring harness connectors and remove the old faulty SAM module.
Install the new replacement SAM module and firmly plug back all connectors.
Reconnect the vehicle battery.
Mandatory SCN online programming/coding with Mercedes-Benz dedicated diagnostic tool Xentry/DAS to match the vehicle's VIN.
After installation and programming, test all rear body functions such as rear lights, door locks, and tailgate to ensure they work normally.

Note: The SAM module is not plug-and-play. Professional programming and matching are required after installation to work properly.

Full OEM Part Number & Amazon ASIN Correspondence Table

OEM Part Number	Amazon ASIN	Product Name	Fits For	Price (USD)
A1649004500	--	Rear Signal Acquisition SAM Control Module	Mercedes GL450 Base Sport Utility 4-Door 2007-2009	369.00
A1649006700	--	Rear Signal Acquisition SAM Control Module	Mercedes ML350 4Matic Sport Utility 4-Door 2006-2010; R350 Bluetec 4Matic Wagon 4-Door 2010-2012; ML320 Bluetec 4Matic Sport Utility 4-Door 2009; GL350 Bluetec 4Matic Sport Utility 4-Door 2010-2012	369.00
A1644405541	--	Rear Signal Acquisition SAM Control Module	Mercedes ML350 4Matic Sport Utility 4-Door 2006-2010; ML320 Bluetec 4Matic Sport Utility 4-Door 2009	369.00
A1649006900	--	Rear Signal Acquisition SAM Control Module	Mercedes ML350 4Matic Sport Utility 4-Door 2006-2010	369.00
A1649005401	--	Rear Signal Acquisition SAM Control Module	Mercedes ML350 4Matic Sport Utility 4-Door 2006-2010; GL320 Bluetec 4Matic Sport Utility 4-Door 2009	369.00
A1649005101	--	Rear Signal Acquisition SAM Control Module	Mercedes ML350 4Matic Sport Utility 4-Door 2006-2010	369.00
A1645408845	--	Rear Signal Acquisition SAM Control Module	Mercedes ML350 4Matic Sport Utility 4-Door 2006-2010	369.00
A1644405101	--	Rear Signal Acquisition SAM Control Module	Mercedes ML320 Bluetec 4Matic Sport Utility 4-Door 2009	369.00
A1644404001	--	Rear Signal Acquisition SAM Control Module	Mercedes ML320 Bluetec 4Matic Sport Utility 4-Door 2009	369.00
A1649004801	--	Rear Signal Acquisition SAM Control Module	Mercedes GL320 Bluetec 4Matic Sport Utility 4-Door 2009; ML350 4Matic Sport Utility 4-Door 2006-2010	369.00

Note: Due to Amazon page parsing failure, some ASIN information cannot be obtained temporarily. The above price is unified based on the available product information, and the actual price shall prevail on the Amazon page.